Long-Term Outcome of Steroid-Resistant Nephrotic Syndrome in Children
نویسندگان
چکیده
منابع مشابه
Children with Steroid-resistant Nephrotic Syndrome: a Single-Center Study
Background and Aim: Steroid-resistant nephrotic syndrome (SRNS) accounts for 10%-20% of all cases of idiopathic nephrotic syndrome. These patients are at risk of developing end-stage renal disease. The aim of this study was to determine the demographic characteristics, renal biopsy findings, response to immunosuppressive treatment, and prognosis in pediatric patients with SRNS.Materials and Met...
متن کاملManagement and outcome of steroid-resistant nephrotic syndrome in children.
INTRODUCTION Steroid-resistant nephrotic syndrome (SRNS) is uncommon in children, but often leads to ESRD. We report our experience with SRNS and its treatments and outcomes. MATERIALS AND METHODS We assessed 73 children with SRNS admitted to Ali Asghar Children Hospital in Tehran, Iran. Their clinical presentations, treatment, and disease courses were reviewed. The mean follow-up duration wa...
متن کاملChildren with Steroid-resistant Nephrotic Syndrome: Long-term Outcomes of Sequential Steroid Therapy.
OBJECTIVE This study aimed to investigate the long-term outcomes in children with steroid-resistant nephrotic syndrome (SRNS), who received methylprednisolone pulse therapy (MPT)-based sequential steroid therapy. In particular, we aimed to observe whether these patients had a high risk of adverse events. METHODS We conducted a retrospective study over a 5-year period. The long-term outcomes f...
متن کاملLong-Term Outcomes in Children with Steroid-Resistant Nephrotic Syndrome Treated with Calcineurin Inhibitors
BACKGROUND Steroid-resistant nephrotic syndrome (SRNS) is an important cause of chronic kidney disease (CKD) in children that often progresses to end-stage renal disease (ESRD). Calcineurin inhibitors (CNIs) have been shown to be effective in inducing short-term remission in some patients with SRNS. However, there are little data examining their long-term impact on ESRD progression rates. MET...
متن کاملLong-term outcome of children with steroid-sensitive idiopathic nephrotic syndrome.
I n children, the most frequent glomerular disease is idiopathic nephrotic syndrome, which is defined by the combination of a nephrotic syndrome and nonspecific histologic abnormalities of the kidney including minimal changes, FSGS, and diffuse mesangial proliferation. The term minimalchange disease has become synonymous with steroid-sensitive idiopathic nephrotic syndrome, although renal biops...
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ژورنال
عنوان ژورنال: Journal of the American Society of Nephrology
سال: 2017
ISSN: 1046-6673,1533-3450
DOI: 10.1681/asn.2016101121